Mitral valve regurgitation — also called mitral regurgitation, mitral insufficiency or mitral incompetence — is a condition in which your heart's mitral valve doesn't close tightly, allowing blood to flow backward in your heart. Thus, blood can't move through your heart or to the rest of your body as efficiently, making you feel tired or out of breath.

Heart disease, also called Heart and blood vessel disease, describes a range of conditions that affect your heart. There are many diseases that are categorized as heart disease, including coronary artery disease, arrhythmias (heart rhythm problems, and congenital heart defects (heart defects you are born with), among many others.
According to the World Health Organization and the CDC, Heart Disease is the leading cause of death in the US, UK, Canada and Australia¹. Currently, 26.6 million US adults (11.3% of the adult population) is diagnosed with Heart Disease. 23.5% of all deaths in the US today are caused by heart disease².